JULÄINE™

Regenerate your skin from within with JULAINE.

JULÄINE™ is the latest innovation in regenerative aesthetics, designed to rejuvenate, firm, and refine your skin by stimulating its natural collagen production.

Developed in Sweden by Nordberg Medical, JULÄINE™ offers a subtle yet transformative approach to rejuvenation, improving skin quality over time without adding artificial volume.

To find out more about JULÄINE™ treatments and to book a consultation, please don’t hesitate to contact our clinics in London, Harley Street, in Stoke Poges, Buckinghamshire and in Northampton, Bournemouth & Lymington.

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Julaine treatment at The Cosmetic Skin Clinic in London Harley Street, Bucks, Bournemouth

Julaine treatment process

What is JULÄINE™?

JULÄINE™ is a collagen bio-activator made from Poly-L-Lactic Acid (PLLA), a biocompatible and biodegradable substance used safely in aesthetic medicine for over 25 years. Unlike traditional fillers that add instant volume, JULÄINE™ works deep within the skin to stimulate your body’s own collagen production, gradually improving firmness, tone, and texture.

How does JULÄINE™ work?

Once injected, JULÄINE™ releases PLLA microspheres into the skin, where they gently activate fibroblasts – the cells responsible for collagen synthesis. This process rebuilds your skin’s internal support network, tightening and smoothing the skin from within.

Over time, the PLLA naturally dissolves, leaving behind new collagen that strengthens the skin’s structure for long-lasting rejuvenation.

Results develop progressively over several months and can last up to 12–24 months, giving natural improvements that evolve beautifully and subtly.

Treatment Benefits of JULÄINE™

JULÄINE™ works with your skin’s natural renewal process to improve:

  • Fine lines and wrinkles
  • Skin firmness and elasticity
  • Laxity and sagging
  • Overall skin quality and texture
  • Radiance and hydration

JULÄINE™ treatment results develop gradually over several months as new collagen forms, giving natural rejuvenation without overcorrection.

JULÄINE™ Treatments

This regenerative treatment is ideal for anyone seeking natural, long-term improvement in skin quality and structure. It effectively addresses multiple concerns, including:

  • Fine lines and wrinkles: Smooths and softens facial lines over time
  • Loss of firmness: Rebuilds skin strength and elasticity
  • Laxity and sagging: Lifts and tightens for a more defined appearance
  • Dull or uneven skin: Restores radiance and hydration

Areas that can be treated with JULÄINE™

Why choose The Cosmetic Skin Clinic for your JULÄINE™ treatment?

At The Cosmetic Skin Clinic, we are recognised UK leaders in non-surgical rejuvenation and regenerative aesthetics. Our practitioners combine clinical expertise with artistry to deliver safe, balanced, and natural-looking results. Every JULÄINE™ treatment is performed using advanced injectable techniques to ensure optimal comfort, precision, and effectiveness. We take a personalised approach to every patient, tailoring your treatment plan to your unique facial structure and skin goals. Our reputation for excellence is built on consistent patient satisfaction, with a 96% patient satisfaction score and 5-star Trustpilot rating, reflecting our commitment to exceptional care and beautiful, natural outcomes.

To find out more about our JULÄINE™ treatments or to book a consultation, please complete our online contact form.

JULÄINE™

Before & Afters

FAQ

JULÄINE™ represents a new standard in regenerative biomaterial design. This PLLA-based bio-activator is both biocompatible and biodegradable, working beneath the surface to deliver progressive, long-lasting facial rejuvenation. By stimulating natural collagen regeneration, it helps to smooth wrinkles, tighten the skin, and restore youthful structure over time.

Each vial of JULÄINE™ contains:

  • 150 mg of Poly-L-Lactic Acid microspheres – the active polymer responsible for stimulating collagen production.

  • 45 mg of Sodium Carboxymethylcellulose – a suspending agent that provides stability and optimal viscosity.

  • 145 mg of Non-pyrogenic Mannitol – a bulking and hydrating agent that enhances the product’s reconstitution and ensures smooth, even application.

JULÄINE™ helps to smooth fine lines and wrinkles while delivering an overall tightening and lifting effect to the skin.

A standard treatment course includes three sessions, spaced 2-4 weeks apart. Results develop gradually, with the full rejuvenating effect visible around three months after completing your treatment course.

Following treatment, it’s normal to experience mild swelling, tenderness, or occasional bruising at the injection sites. These effects are temporary and typically subside within a few days.

The results of JULÄINE™ are long-lasting, with improvements maintained for 12-24 months, depending on your skin condition and lifestyle.

JULÄINE™ is CE-marked, ensuring the highest standards of safety and quality assurance.

Developed and manufactured in Sweden, JULÄINE™ offers full product traceability and consistent production excellence. Each batch is subject to rigorous quality control procedures to guarantee reliability and performance.

According to a recent scientific publication, early findings from an ongoing safety study confirm that JULÄINE™ demonstrates a proven safety profile when administered under appropriate clinical conditions.

Results typically last 12-24 months, and cumulative treatments can extend and enhance these benefits.

PLLA (Poly-L-Lactic Acid) is a biodegradable and biocompatible polymer derived from lactic acid, a substance naturally produced by the body.

With a trusted history of over 40 years in medical applications and more than 25 years in aesthetic medicine, PLLA is widely recognised for its safety and effectiveness in stimulating natural collagen production.

As PLLA gradually dissolves within the skin, it breaks down into lactic acid, which the body naturally metabolises into energy, water, and carbon dioxide — ensuring complete biocompatibility and a gentle, natural process of skin renewal.

Lactic acid is a naturally occurring molecule that your body produces, especially during exercise, and it plays a vital role in keeping your skin and tissues healthy.

Beyond being a by-product of movement, lactic acid acts as a powerful messenger for regeneration. It encourages fibroblasts to produce fresh collagen, strengthening the skin from within and restoring its youthful resilience.

It also promotes the formation of new blood vessels, improving circulation and nutrient delivery. The result is skin that feels revitalised, firmer, and more radiant, all through your body’s own natural processes.

Most patients find JULÄINE™ treatments comfortable and well tolerated, with no special preparation required. You may experience a brief sensation of mild discomfort during the injections, but this typically subsides quickly.

Our expert practitioners use advanced techniques to ensure your comfort throughout, and most patients are able to resume their normal activities immediately after treatment. 

Following your JULÄINE™ treatment, your practitioner will recommend gentle aftercare to support optimal results.

For the next few days, lightly massage the treated area using your regular facial moisturiser to help evenly distribute the product.

It’s also best to avoid direct sunlight, UV exposure, and extreme temperatures (such as saunas or steam rooms) until any initial redness or swelling has completely settled.

These simple steps will help your skin heal beautifully and ensure the most natural-looking outcome.

Results typically last between 12 and 24 months, depending on your skin condition, age, and lifestyle. Maintenance sessions can help prolong your results.

A standard treatment course includes three sessions, spaced 2-4 weeks apart. Your practitioner will create a bespoke plan tailored to your skin needs and aesthetic goals.

Most patients experience only mild redness, swelling, or tenderness at the injection sites, which typically settles within a few days. Occasional bruising may occur but is temporary and can be easily concealed with light make-up.

Both treatments use Poly-L-Lactic Acid to stimulate collagen production. However, JULÄINE™ is formulated with LaSynPro™ technology, which ensures highly uniform microspheres for smoother integration and more even, natural-looking results. It represents the next generation of PLLA-based bio-activators.

You may notice an improvement in skin radiance and texture within a few weeks, with the full results developing gradually over 2–3 months as new collagen is produced.

The cost of JULÄINE™ treatment varies depending on the treatment area and number of sessions required. Your practitioner will provide a personalised quote during your consultation based on your individual needs.

Yes. In addition to the face, JULÄINE™ can be used to rejuvenate the neck, décolletage, and hands, improving firmness, texture, and elasticity in these delicate areas.

JULÄINE™ is not a filler. It is a collagen bio-activator that works by stimulating your skin’s own regenerative processes to rebuild structure and restore youthful firmness, without adding instant volume.

Yes. JULÄINE™ can be safely combined with complementary treatments such as anti-wrinkle injections, Profhilo®, or energy-based rejuvenation procedures to enhance overall results and improve skin quality.

Downtime is minimal. Most patients return to daily activities immediately. Mild swelling or bruising may occur but usually resolves within a few days.

JULÄINE™ is developed and manufactured by Nordberg Medical in Sweden, a leader in regenerative aesthetics known for scientific innovation and product excellence.

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