Ameela London & Buckinghamshire

In the field of injectable skin boosters there is a new addition known as Ameela. It is the latest biosimulator injectable treatment that has been rightfully generating buzz, as seen on This Morning.

Ameela, formerly known as Nucleadyn, is considered to be a skinbooster that provides an additional boost. This collagen boosting injection treatment aims to enhance skin structure, increase collagen, elastin, and hydration.

At The Cosmetic Skin Clinic, we are excited about Ameela and its promising results of showing up to 22.5% less wrinkles after just three sessions. Ameela collagen booster treatment is available at our clinics in London and Bucks.

Medically reviewed by the MDT Advisory Committee for The Cosmetic Skin Clinic, London and Bucks. Last reviewed on 18th December 2023.

ameela London and Buckinghamshire - Dr Johanna Ward

Through innovative technology, Ameela is formed of filtered and purified polyneuclotide molecules. Polynucleotides are shortened fractions of DNA that can be naturally found within the body. These chains have the ability to induce regenerative changes at the cellular level. They are effectively used in regenerative medicine. Polynucleotides can cause the body to repair itself, facilitating the body being the treatment. When the Ameela treatment is applied, it results in indepth skin rejuvenation.

“Polynucleotides work by increasing hydration in the tissue, reducing free radical damage via powerful bio stimulation of collagen, elastin, and hyaluronic acid. Polynucleotides are the building blocks of DNA so it’s taking bio-regeneration to the molecular level.” – Dr Johanna Ward – MA(OXON) MBBS DRCOG MRCGP Dip Clinical Dermatology – Cosmetic Doctor

Ameela treatment areas

Ameela collagen boosting treatment can be used to treat a number of areas including:

  • The face
  • Neck
  • Hair
  • Hands

Of these areas, Ameela polynucleotides can treat the following:

Ameela Polynucleotides benefits:

  • Restores skin tone and elasticity
  • Regenerates tissue
  • Triggers and improves tissue regulation
  • Targets free radicals and oxidative stress
  • Deeply moisturising
  • Improves the circulatory system
  • Accelerates wound healing
  • Repairs severely damaged skin
  • Reduces pigmentation and scars

How Ameela Polynucleotides treatment works

Ameela skin booster injectable treatment utilises advanced technology and is made up of polymerised polynucleotides, which are organic molecules that are vital in anti-aging processes and widely used in regenerative medicines. The innovative formula ensures maximum compatibility and effectiveness, providing optimal results for your skin.

Fibroblast cells are responsible for producing collagen, a protein that provides structure and support to the skin. As we age, the production of collagen decreases, leading to wrinkles and sagging skin. Once injected, Polynucleotides can kickstart the fibroblast cells to stimulate the release of healthy collagen, which can increase skin firmness and improve skin tone. Polynucleotides can trigger the wound-healing effect in our skin to repair any scar tissue we may have. When injected into targeted areas, Ameela works innovatively and effectively to restore skin firmness, boost collagen and elasticity while protecting against cellular damage and free radicals. Thanks to its maximum compatibility, positive effects such as a visible lift in skin structure can be quickly noticed, providing a more youthful and rejuvenated appearance.

To find out more about the Ameela collagen stimulating treatment and other treatments that can be combined with it, please get in touch with our London or Buckinghamshire expert practitioners.

“Very excited, in the 20 years I have been in the aesthetics industry, never has there been an injectable for underneath the eye area that we can inject so close to the eye, to rejuvenate this delicate area. However, this new innovation is not only for the eyes but for the whole skin with other formulations to treat the whole face and neck, as well as hair. Ameela (polynucleotides) helps to promote collagen type 1 which helps to reduce wrinkles it also clears up the free radical damage that goes on inside our skin, restores elasticity, increases blood vessels, lifts, and plumps.” – Mr Lee Garrett – RN BSc NMP Snr Aesthetic Practitioner & Clinical Lead


Ameela (formerly Nucleadyn) is the newest biostimulator injectable treatment designed to revitalise your skin. This powerful formula can effectively restore skin firmness and elasticity while protecting it against cellular damage and free radicals. Say goodbye to premature aging and hello to healthy, rejuvenated skin.

Some patients are able to see the first signs of improvement from 7-10 days post first treatment. Full and best results will be visible after you have had all three Ameela sessions. We recommend the three sessions because it has shown there are 22.5% less wrinkles after 3 sessions.

Ameela results can last up to 6-9 months. After which point, we always recommend booking in for a maintenance appointment to add longevity to your results.

At The Cosmetic Skin Clinic, dependent on the patient and the concern area/s, we recommend having three Ameela treatments a month apart from one another.

To maintain your results, we also recommend a top-up appointment every 9 months for best result maintenance.

With Ameela polynucleotides treatments, the downtime is very minimal at 2-4 hours dependent on how sensitive your skin is.

Ameela treatment time is usually 10 minutes per treatment area.

The Ameela collagen boosting injection will be administered in a gentle and careful manner that prioritises comfort and aims to prevent any potential pain or discomfort. To further prevent any discomfort, our practitioners will apply a numbing cream pre-treatment for 10 minutes.

Ameela collagen booster is suitable for both men and women. It is best suited for those who:

  • Are showing evidence of wrinkles and fine lines, and are advanced in age
  • Are experiencing signs of premature ageing
  • Have hyperpigmentation
  • Have very dehydrated skin
  • Have skin laxity

If you are allergic to fish, then unfortunately Ameela is not the treatment for you. Ameela uses animal-based polynucleotides that are derived from salmon, specifically the sperm cells of salmon.

Polynucleotides are biostimulators, meaning they have the ability to jump-start the skin’s regeneration process. Rather than simply hydrating the skin, they act more like nourishment or medication for the cells, encouraging them to produce collagen and elastin in a more effective manner. Additionally, they can improve the extra cellular matrix, which is the layer of the skin in which fibroblasts reside. Furthermore, they have anti-inflammatory properties.

Ameela does not include hyaluronic acid in its composition. However, it enhances the production of your body’s own hyaluronic acid and amplifies the effect of any other hyaluronic acid that may have been administered to you by up to 40%.

They both have a similar function promise of working on the skins condition, rather than adding volume like dermal fillers do. However, they are not the same. Ameela is a bio-stimulant gel consisting of polynucleotides, whereas Profhilo consists of a mixture of pure concentrated hyaluronic acid.

Both are bio-stimulators/bio-remodelling in their own way. Sunekos consists of a potent cocktail of hyaluronic acid (HA) and amino acids, whereas Ameela is a bio-stimulant gel consisting of polynucleotides.

You can get your Ameela treatment at either of The Cosmetic Skin Clinic’s London or Buckinghamshire clinic.

  • The London clinic is situated at 8 Devonshire Place, Marylebone, London W1G 6HP.
  • The Buckinghamshire clinic is located in Stoke Poges at 84 Rogers Lane, Slough SL2 4LF.

Ameela London – The Cosmetic Skin Clinic is conveniently situated close to Oxford Circus and Baker Street tube stations In London. Additionally, trains are accessible from Paddington and Kings Cross St Pancras stations.

Our London clinic is conveniently accessible from various surrounding boroughs, including:

Battersea, Bayswater, Belgravia, Chelsea, Earls Court, Fitzrovia, Fulham, Knightsbridge, Marylebone, Mayfair, Notting Hill, Primrose Hill, Regents Park, Soho, South Kensington, St Johns Wood, Green Park, Hampstead, Highgate, Holland Park, Hyde Park, Islington, Kensington, Kings Road, Victoria, West Brompton, Westminster and West End.

The nearest tube stations to our London clinic.

Ameela Buckinghamshire – The Cosmetic Skin Clinic in Stoke Poges, Bucks, is conveniently situated near Gerrards Cross-Chiltern Railway and Slough-First Great Western stations. The clinic is easily accessible from Wembley, Richmond, Kingston upon Thames, and the Surrey area via quick transport links with major roads such as the M25, M4, M40, and A40.

Directions to our Stoke Poges, Buckinghamshire clinic.

Book your consultation here or give our London or Buckinghamshire clinic a call on 0343 253 8240.

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