GLP-1s and Facial Changes: How Dr Victoria Manning Supports Patients After Weight Loss

In the latest issue of Aesthetics Journal, Dr Victoria Manning explores one of the most topical trends in aesthetics today – the facial changes that occur after rapid weight loss, particularly in patients using GLP-1 medications such as Ozempic®, Wegovy® and Mounjaro®.

While these medications can be life-changing for health and wellbeing, patients often notice new concerns such as skin laxity, mid-face volume loss and thinning skin. For many women, perimenopause compounds these changes, as natural oestrogen decline further reduces collagen and elastin. As Dr Manning explains:

“A lot of my GLP-1 patients are also perimenopausal. They’re losing oestrogen, which further reduces collagen and elastin. It’s a double hit. Skin becomes thinner and laxer, and without intervention, it can be really hard to manage.”

Why Weight Loss Affects the Face

As the body loses fat, the natural volume that once supported facial structure diminishes. This can create hollowing in the cheeks, sagging around the jawline, and an overall appearance that may not reflect how healthy and energetic a patient feels on the inside. Hormonal changes at midlife can intensify these facial volume loss effects, making skin looser and more difficult to tighten without treatment.

Advanced Treatments Dr Manning Recommends

In the article, Dr Manning shares the range of clinically proven treatments she uses to restore balance and skin quality after weight loss. These include:

  • Sculptra® – a collagen-stimulating injectable that gradually restores volume and structure.
  • Ellansé® – a biostimulatory injectable that encourages long-term collagen regeneration.
  • Restylane® Skinboosters – designed to improve hydration, elasticity and skin texture.
  • Microneedling – to remodel the skin and stimulate new collagen
  • Ultherapy® – a focused ultrasound treatment to lift and define the lower face.
  • Julaine – a collagen-stimulating injectable that delivers progressive tightening.

Putting Safety First

Dr Manning is clear that patient selection is just as important as treatment choice. She always prioritises safety and ensures that every plan is tailored to the individual:

“I don’t treat anyone with autoimmune conditions – such as Graves’ disease, thyroiditis or psoriasis. It’s just common sense, in my opinion.”

Why Choose The Cosmetic Skin Clinic?

  • Trusted experts: Dr Victoria Manning and our team are at the forefront of non-surgical facial rejuvenation.
  • Natural results: We focus on subtle, restorative treatments that refresh the face without changing what makes each patient unique.
  • Tailored care: Every treatment journey is bespoke, carefully planned around your goals, skin health and lifestyle.

Book Your Consultation

For patients who have experienced rapid weight loss with GLP-1s and want to restore balance and confidence in their appearance, Dr Victoria Manning offers advanced, personalised treatment plans. At The Cosmetic Skin Clinic, every journey begins with a detailed consultation to explore the safest and most effective options for you.

Book your consultation today and take the first step towards feeling confident in your reflection once again.

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